Combining fetal nuchal fold thickness with second-trimester biochemistry to screen for trisomy 21
نویسندگان
چکیده
منابع مشابه
The effect of nuchal cord on nuchal fold thickness measured in the second trimester.
PURPOSE To find out whether nuchal cord causes an effect on the nuchal skin fold thickness (NFT) measurements, or not. PATIENTS AND METHODS A total of 242 fetuses with normal outcomes that had undergone detailed second trimester US scan between 18 and 24 weeks of gestation were included in the study. NFT measurements were made on axial cranial US images passing through the cerebellum and cavu...
متن کاملScreening for trisomy 21 in monochorionic twins by measurement of fetal nuchal translucency thickness.
OBJECTIVE To determine whether in screening for trisomy 21 by measurement of fetal nuchal translucency (NT) thickness in monochorionic twin pregnancies it is preferable to use the higher, smaller or average NT. METHODS We retrospectively examined 769 monochorionic twin pregnancies that had undergone NT screening. The selection criteria were that first, in each pregnancy both fetuses were aliv...
متن کاملFirst trimester risk assessment for trisomy 21 in twin pregnancies combining nuchal translucency and first trimester biochemical markers.
OBJECTIVE The aim is to describe the performance of first-trimester combined risk assessment in twin pregnancies. METHODS Maternal serum free beta-human chorionic gonadotrophin and pregnancy-associated plasma protein A (PAPP-A) were determined at 8 to 12 weeks and fetal nuchal translucency (NT) was measured at 11 to 13+6 weeks. The individual risk was estimated for each fetus using the combin...
متن کاملP-226: Non-Invasive Prenatal Screening for Fetal Chromosomal Anomalies in South of Iran
Background: Prenatal diagnosis for Fetal Chromosomal anomalies currently relies on assessment of risk followed by a combination of biochemical and nuchal translucency. Trisomy 21 is the most common trisomy that is associated with intellectual disability. Pregnant women who receive a prenatal diagnosis of trisomy 21 currently have the option of continuing or terminating their pregnancy, but no f...
متن کاملA first trimester trisomy 13/trisomy 18 risk algorithm combining fetal nuchal translucency thickness, maternal serum free beta-hCG and PAPP-A.
This study examines 45 cases of trisomy 13 and 59 cases of trisomy 18 and reports an algorithm to identify pregnancies with a fetus affected by trisomy 13 or 18 by a combination of maternal age fetal nuchal translucency (NT) thickness, and maternal serum free beta-hCG and PAPP-A at 11-14 weeks of gestation. In this mixed trisomy group the median MoM NT was increased at 2.819, whilst the median ...
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ژورنال
عنوان ژورنال: Ultrasound in Obstetrics and Gynecology
سال: 2007
ISSN: 0960-7692,1469-0705
DOI: 10.1002/uog.5187